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Invitrogen™ GHSR Polyclonal Antibody
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Catalog No. PIPA528752
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100 μL
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PIPA528752 100 μL
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Catalog No. PIPA528752 Supplier Invitrogen™ Supplier No. PA528752
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, PC-3, U87-MG, SK-N-SH, mouse hypothalamus, mouse brain, rat brain. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations to the gene can cause isolated partial growth hormone deficiency.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GHSR
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Ghsr
Gene Accession No. Q92847, Q99P50
Gene Alias C530020I22Rik; GHDP; GH-releasing peptide receptor; Ghrelin receptor; GHRP; Ghrp receptor; GHS receptor; GHSR; GHS-R; G-protein coupled receptor; growth hormone secretagogue receptor; growth hormone secretagogue receptor type 1
Gene Symbols Ghsr
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Extracellular domain of human GHS-R1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 208188, 2693
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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