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Ginkgolide B

Catalog No. AAJ60646MA
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Catalog No. AAJ60646MA Supplier Thermo Scientific Chemicals Supplier No. J60646MA
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Description

Platelet-Activating Factor (PAF) antagonist | CAS: 15291-77-7 | C20H24O10 | 424.402 g/mol

Ginkgolide B is used as a potent PAF-R antagonist. Ginkgolide B speeds up PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Additionally, this compound has been reported to inhibit neutrophil degranulation in vitro. Inhibits superoxide production in vitro and inhibits bronchoconstriction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ginkgolide B is used as a potent PAF-R antagonist. Ginkgolide B speeds up PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Additionally, this compound has been reported to inhibit neutrophil degranulation in vitro. Inhibits superoxide production in vitro and inhibits bronchoconstriction.

Solubility
Soluble in DMSO. Slightly soluble in water and ethanol

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 15291-77-7
Molecular Formula C20H24O10
Molecular Weight (g/mol) 424.402
MDL Number MFCD05662347
InChI Key SQOJOAFXDQDRGF-WVXYHUDCSA-N
Synonym sqojoafxdqdrgf-maggbrlhsa-n
PubChem CID 132470872
SMILES CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O

Specifications

Color White
Quantity 10 mg
Merck Index 14,4426
Solubility Information Soluble in DMSO; Slightly soluble in water and ethanol
Formula Weight 424.4
Physical Form Powder
Chemical Name or Material Ginkgolide B

Safety and Handling

TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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