Ginkgolide B

Description

Platelet-Activating Factor (PAF) antagonist | CAS: 15291-77-7 | C20H24O10 | 424.402 g/mol

Ginkgolide B is used as a potent PAF-R antagonist. Ginkgolide B speeds up PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Additionally, this compound has been reported to inhibit neutrophil degranulation in vitro. Inhibits superoxide production in vitro and inhibits bronchoconstriction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ginkgolide B is used as a potent PAF-R antagonist. Ginkgolide B speeds up PAF hydrolysis by promoting PAF-AH I α2 homodimer activity. Additionally, this compound has been reported to inhibit neutrophil degranulation in vitro. Inhibits superoxide production in vitro and inhibits bronchoconstriction.

Solubility
Soluble in DMSO. Slightly soluble in water and ethanol

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 15291-77-7
• Molecular Formula: C20H24O10
• Molecular Weight (g/mol): 424.402
• MDL Number: MFCD05662347
• InChI Key: SQOJOAFXDQDRGF-WVXYHUDCSA-N
• Synonym: sqojoafxdqdrgf-maggbrlhsa-n
• PubChem CID: 132470872
• SMILES: CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O

• Color: White
• Quantity: 10 mg
• Merck Index: 14,4426
• Solubility Information: Soluble in DMSO; Slightly soluble in water and ethanol
• Formula Weight: 424.4
• Physical Form: Powder
• Chemical Name or Material: Ginkgolide B

Safety and Handling

TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only