Learn More
Description
The MIH44 monoclonal antibody specifically binds to Glucocorticoid-induced TNF-related Ligand (GITR Ligand). The GITR Ligand protein is encoded by the Tnfsf18 (Tumor necrosis factor ligand superfamily member 18) gene. The GITR Ligand is a type II transmembrane protein that is expressed on endothelial cells and antigen presenting cells, including B cells, macrophage and dendritic cells. The GITR Ligand reportedly costimulates T cell activation and reverses CD4+CD25+ Treg cell-mediated suppression by interaction with its cognate receptor, GITR that is expressed by these cells.
Specifications
Specifications
| Antigen | GITR Ligand |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MIH44 |
| Conjugate | R718 |
| Host Species | Mouse |
| Quantity | 50 μg |
| Regulatory Status | RUO |
| Primary or Secondary | Primary |
| Target Species | Mouse |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.