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GITR Ligand Mouse, anti-Mouse, R718, Clone: MIH44, BD OptiBuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 752033

Catalog No. BDB752033


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Description

Description

The MIH44 monoclonal antibody specifically binds to Glucocorticoid-induced TNF-related Ligand (GITR Ligand). The GITR Ligand protein is encoded by the Tnfsf18 (Tumor necrosis factor ligand superfamily member 18) gene. The GITR Ligand is a type II transmembrane protein that is expressed on endothelial cells and antigen presenting cells, including B cells, macrophage and dendritic cells. The GITR Ligand reportedly costimulates T cell activation and reverses CD4+CD25+ Treg cell-mediated suppression by interaction with its cognate receptor, GITR that is expressed by these cells.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

GITR Ligand
Monoclonal
R718
50 μg
Primary
Refrigerate Upon Arrival
Flow Cytometry
MIH44
Mouse
RUO
Mouse
Liquid
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