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GITR Ligand Mouse, anti-Mouse, R718, Clone: MIH44, BD OptiBuild™

Catalog No. BDB752033 Shop All BD Biosciences Products
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Catalog No. BDB752033 Supplier BD Biosciences Supplier No. 752033
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Mouse Monoclonal Antibody

The MIH44 monoclonal antibody specifically binds to Glucocorticoid-induced TNF-related Ligand (GITR Ligand). The GITR Ligand protein is encoded by the Tnfsf18 (Tumor necrosis factor ligand superfamily member 18) gene. The GITR Ligand is a type II transmembrane protein that is expressed on endothelial cells and antigen presenting cells, including B cells, macrophage and dendritic cells. The GITR Ligand reportedly costimulates T cell activation and reverses CD4+CD25+ Treg cell-mediated suppression by interaction with its cognate receptor, GITR that is expressed by these cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen GITR Ligand
Applications Flow Cytometry
Classification Monoclonal
Clone MIH44
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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