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Invitrogen™ GKN1 Polyclonal Antibody
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Catalog No. PIPA523309
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100 μg
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Catalog No. Quantity
PIPA523309 100 μg
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Catalog No. PIPA523309 Supplier Invitrogen™ Supplier No. PA523309
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Description

Rabbit Polyclonal Antibody

The amino acid sequence used as immunogen is 100% homologous in chimpanzee and dog, 94% homologous in mouse and cow, 88% homologous in rat and 77% homologous in chicken.

Gastrokine 1, also known as GKN1 and CA11, is a 185 amino acid containing secreted protein belonging to the gastrokine family with a BRICHOS domain and an asn-rich region. GKN1 (also known as an antioncogene) is reported to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. Differential display of normal and cancerous gastric tissue suggested that this protein is predominantly expressed in stomach and the expression is down-regulated to considerable frequency in cancer tissue or gastric cancer cell lines examined. This extra cellular protein is co-secreted with mucins and is a signaling growth factor with mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GKN1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene GKN1
Gene Accession No. Q8HYA9, Q9NS71
Gene Alias 18 kDa antrum mucosa protein; 2200002K21Rik; Amp18; AMP-18; Amp18; gastrokine; BRICD1; BRICHOS domain containing 1; Ca11; FOV; foveolin; gastrokine 1; gastrokine-1; Gkn1; Protein CA11; Protein CA11 homolog; UNQ489/PRO1005
Gene Symbols GKN1
Host Species Rabbit
Immunogen The portions of amino acids range between 100-150 of human GKN1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100061374, 100502561, 56287
Target Species Human, Monkey, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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