Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA583664

Invitrogen™ GLE1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA583664
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA583664 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA583664 Supplier Invitrogen™ Supplier No. PA583664
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: RCWETLKALR SSDKGRLCYY RDWLLRREDV LEECMSLPKL SSYSGWVVEH VLPHMQENQP LSETSPSSTS ASALDQPSFV PKSPDAS Highest antigen sequence indentity to the following orthologs: Mouse - 67%, Rat - 68%.

The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLE1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GLE1
Gene Accession No. Q53GS7
Gene Alias 4933405K21Rik; AA553313; GLE1; GLE1 RNA export mediator; GLE1 RNA export mediator (yeast); GLE1 RNA export mediator homolog; GLE1 RNA export mediator-like (yeast; GLE1, RNA export mediator; GLE1L; GLE1-like protein; GLE1-like, RNA export mediator; hGLE1; LCCS; LCCS1; Nucleoporin GLE1
Gene Symbols GLE1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GLE1. Recombinant protein control fragment (Product #RP-98405).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2733
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.