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Invitrogen™ GLI3 Polyclonal Antibody
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Catalog No. PIPA595052
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100 μg
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PIPA595052 100 μg
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Catalog No. PIPA595052 Supplier Invitrogen™ Supplier No. PA595052
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Testis Tissue, A549 Cell, SW620 Cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLI3
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene GLI3
Gene Accession No. P10071, Q61602
Gene Alias ACLS; add; AI854843; anterior digit pattern deformity; AU023367; Bph; brachyphalangy; extra toes; GCPS; GLI family zinc finger 3; GLI family zinc finger 3 L homeolog; gli3; GLI3 C-terminally truncated form; GLI3 form of 190 kDa; GLI3 form of 83 kDa; GLI3 full length protein; GLI3 full-length protein; gli3.L; GLI3-190; GLI3-83; GLI3FL; GLI-Kruppel family member 3; GLI-Kruppel family member GLI3; GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome); glioma-associated oncogene family zinc finger 3; im:7142603; neural specific DNA binding protein; neural-specific DNA-binding protein xGLI3; oncogene GLI3; PAPA; PAP-A; PAPA1; PAPB; Pdn; PHS; polydactyly Nagoya; PPDIV; Transcriptional activator GLI3; Transcriptional repressor GLI3R; XELAEV_18031191mg; xgli3; xGLI-3; Xt; Zinc finger protein GLI3; zinc finger protein GLI3; transcriptional activator GLI3; zinc finger transcription factor Gli3
Gene Symbols GLI3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human Gli3 (40-57aa SNEDESPGQTYHRERRNA).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140588, 14634, 2737
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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