Invitrogen™ GLP-1 Monoclonal Antibody (10), Biotin

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ ABS03310B005

Catalog No. ABS03310B05

Description

ABS 033-10B-005 detects GLP1 from human samples. ABS 033-10B-005 is specific towards the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide. ABS 033-10B-005 has been successfully used in ELISA procedures. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Specifications

• Antigen: GLP-1
• Classification: Monoclonal
• Concentration: 1.00 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01275
• Gene Symbols: GCG
• Immunogen: Synthetic GLP-1(7-17).
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 10
• Conjugate: Biotin
• Gene: GCG
• Gene Alias: GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 2641
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid