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Invitrogen™ GLP-1 Polyclonal Antibody
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Catalog No. PIPA579303
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100 μg
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PIPA579303 100 μg
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Catalog No. PIPA579303 Supplier Invitrogen™ Supplier No. PA579303
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - IHC: mouse pancreas tissue, rat pancreas tissue, human pancreatic cancer tissue.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.
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Specifications

Antigen GLP-1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide
Gene GCG
Gene Accession No. P01275, P06883, P55095
Gene Alias GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
Gene Symbols GCG
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human GLP1 (53-81aa HSQGTFTSDYSKYLDSRRAQDFVQWLMNT).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14526, 24952, 2641
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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