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Invitrogen™ GLT-1 Polyclonal Antibody
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Catalog No. PIPA519706
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100 μg
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Catalog No. Quantity
PIPA519706 100 μg
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Catalog No. PIPA519706 Supplier Invitrogen™ Supplier No. PA519706
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with human based on sequence homology.

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLT-1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide; pH 7.4
Gene SLC1A2
Gene Accession No. P31596, P43006
Gene Alias 1700091C19Rik; 2900019G14Rik; AI159670; Eaat2; EAAT2 variant mEAAT2/5UT5; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; Glt; GLT1; GLT-1; GLT1a; GLT1b; GLT1c; glutamate transporter 1c; glutamate/aspartate transporter II; GLUT-R; HBGT; high affinity glucose transporter; MGLT1; OTTHUMP00000165209; OTTHUMP00000165210; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; solute carrier family 1 member 2; solute carrier family 1, member 2
Gene Symbols SLC1A2
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Rat Glutamate Transporter 1 (EAAT2).
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20511, 29482
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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