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Invitrogen™ GLT-1 Polyclonal Antibody
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PIPA580011 100 μg
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Catalog No. PIPA580011 Supplier Invitrogen™ Supplier No. PA580011
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat brain tissue, mouse brain tissue. IHC: mouse brain tissue, rat brain tissue.

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.
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Specifications

Antigen GLT-1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene SLC1A2
Gene Accession No. P31596, P43004, P43006
Gene Alias 1700091C19Rik; 2900019G14Rik; AI159670; Eaat2; EAAT2 variant mEAAT2/5UT5; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; Glt; GLT1; GLT-1; GLT1a; GLT1b; GLT1c; glutamate transporter 1c; glutamate/aspartate transporter II; GLUT-R; HBGT; high affinity glucose transporter; MGLT1; OTTHUMP00000165209; OTTHUMP00000165210; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; solute carrier family 1 member 2; solute carrier family 1, member 2
Gene Symbols SLC1A2
Host Species Rabbit
Immunogen E.coli-derived human EAAT2 recombinant protein (Position: T461-K574).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20511, 29482, 6506
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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