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Invitrogen™ Glucagon Receptor Polyclonal Antibody
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Catalog No. PA550668
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100 μL
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PA550668 100 μL
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Catalog No. PA550668 Supplier Invitrogen™ Supplier No. PA550668
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total GCGR / Glucagon Receptor protein.

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glucagon Receptor
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene GCGR
Gene Accession No. P30082, P47871, Q61606
Gene Alias GCGR; GGR; GL-R; Glucagon receptor; glucagon receptor perhaps same as Niddm3; GR
Gene Symbols GCGR
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human glucagon receptor.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14527, 24953, 2642
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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