Invitrogen™ Glucagon Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550668

Catalog No. PA550668

Description

The antibody detects endogenous levels of total GCGR / Glucagon Receptor protein.

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.

Specifications

• Antigen: Glucagon Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GCGR
• Gene Alias: GCGR; GGR; GL-R; Glucagon receptor; glucagon receptor perhaps same as Niddm3; GR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14527, 24953, 2642
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.7 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P30082, P47871, Q61606
• Gene Symbols: GCGR
• Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human glucagon receptor.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG