Glutathione Oxidized, MP Biomedicals™

Description

Protects against oxidative damage. Glutathione Oxidized, MP Biomedicals is the oxidised dimeric form of glutathione (GSH), a naturally occuring tripeptide that takes part in the body's detoxification mechanisms.

Acts as a hydrogen acceptor in enzymic determination of NADP and NADPH.

• In vivo, Glutathione disulfide (GSSG) is reduced back to glutathione (GSH) via the NADPH-dependent enzyme glutathione reductase
• The ratio of GSH to GSSG is often used to gauge the level of oxidative stress in cells, with higher concentrations of GSSG implying more oxidative stress

Specifications

Chemical Identifiers

• CAS: 27025-41-8
• Molecular Formula: C20H32N6O12S2
• Molecular Weight (g/mol): 612.63
• MDL Number: MFCD00150701
• InChI Key: YPZRWBKMTBYPTK-IOKZUGQQNA-N
• Synonym: oxiglutatione, glutathione disulfide, gssg, oxidized glutathione, glutathione disulphide, glutathione-ssg, l-glutathione oxidized, oxigluthione, glutathone disulfide, glutathione oxidized
• PubChem CID: 65359
• ChEBI: CHEBI:17858
• IUPAC Name: (2S)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid
• SMILES: N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O

• Melting Point: 178°C (decomposition)(literature)
• pH: 1 to 6
• Quantity: 500 mg
• Solubility Information: Soluble in water (3.3%): Clear, Colorless Solution.
• Optical Rotation: (c=1, water) –85 to –110°
• Formula Weight: 612.64
• Physical Form: Crystalline Powder

Safety and Handling

Recommended Storage

+4°C