Glutathione Reduced, Cell Culture Reagent, ≥98%, MP Biomedicals™

Description

Glutathione Reduced, Cell Culture Reagent, ≥98% is used for protein purification and elutes GST-tagged protein from glutathione agarose.

• Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells.
• It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
• Glutathione is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst.
• Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center.
• Glutathione also forms disulfide bonds with cysteine residues in proteins.
• Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
• Typical Working Concentration: May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Specifications

Chemical Identifiers

• CAS: 70-18-8
• Molecular Formula: C10H17N3O6S
• Molecular Weight (g/mol): 307.321
• MDL Number: MFCD00065939
• InChI Key: RWSXRVCMGQZWBV-WDSKDSINSA-N
• Synonym: glutathione, l-glutathione, glutathion, glutathione-sh, glutinal, isethion, tathion, reduced glutathione, deltathione, neuthion
• PubChem CID: 124886
• ChEBI: CHEBI:16856
• IUPAC Name: (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
• SMILES: C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

• Melting Point: 195°C
• Color: White
• Assay Percent Range: >98%
• Quantity: 5 g
• Solubility Information: 292.5 mg/mL
• Formula Weight: 307.32
• Percent Purity: ≥98%
• Grade: Cell Culture
• Physical Form: Powder
• Chemical Name or Material: Glutathione Reduced, Cell Culture Reagent

Safety and Handling

EINECSNumber	200-725-4
Recommended Storage	Store at +4°C. Store under nitrogen.

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.