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Abcam Gly-Phe beta-naphthylamide, Cathepsin C substrate, 1G

Supplier:  Abcam AB1459141G

Encompass_Preferred

MW 347.41 g/mol, Purity >95%. Substrate for the lysosomal cysteine protease Cathepsin C. Accumulates within the lysosome. Hydrolysis by cathepsin C degrades Gly-Phe-β-naphthylamide into fragments that do not easily diffuse through the lysosomal membrane, leading to a loss of lysosome membrane integrity. Used to study intralysosomal hydrolysis, lysosomal membrane permeability, and the function of cathepsin C. Inhibits the cathepsin-dependent activation of caspase-8.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-5016


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