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Invitrogen™ GLYATL1 Polyclonal Antibody
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Catalog No. PIPA521805
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PIPA521805 100 μL
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Catalog No. PIPA521805 Supplier Invitrogen™ Supplier No. PA521805
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The GLYATL1 gene, also known as Glycine-N-Acyltransferase Like 1, is located on chromosome 11q12.1. This gene encodes a member of the glycine-N-acyltransferase family, which is involved in the detoxification pathway by catalyzing the conjugation of acyl-CoA substrates with glycine. The protein encoded by GLYATL1 is localized to the endoplasmic reticulum and is implicated in various cellular processes, including xenobiotic metabolism and mitochondrial glutamine metabolism. Studies have shown that the expression levels of GLYATL1 are significantly associated with cancer prognosis. For example, decreased expression of GLYATL1 has been linked to poor prognosis in patients with clear cell renal cell carcinoma (ccRCC). Furthermore, differential expression analysis has identified GLYATL1 as a potential biomarker in prostate cancer, suggesting its utility in cancer diagnostics and treatment strategies. The gene comprises multiple exons and undergoes alternative splicing, resulting in various transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLYATL1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene GLYATL1
Gene Accession No. Q969I3
Gene Alias acyl-CoA:glycine N-acyltransferase-like protein 1; GATF-C; Glutamine N-acyltransferase; GLYATL1; Glycine N-acyltransferase-like protein 1; glycine-N-acyltransferase like 1; glycine-N-acyltransferase-like 1; GNAT; RGD1564894; uncharacterized protein LOC309227
Gene Symbols GLYATL1
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 73 and 302 of GLYATL1 (Uniprot ID#Q969I3).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 92292
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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