Glyoxylic acid monohydrate, 97%

Description

CAS: 563-96-2 | C2H4O4 | 92.05 g/mol

Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glyoxylic acid is a reagent for sulfinylmaleate synthesis. It is one of the chemicals used in the Hopkins Cole reaction. It is involved to check the presence of tryptophan in proteins. It is condensed with urea and 1,2-diaminobenzene to form heterocycles. It also undergoes Friedel-Crafts and cyclocondensation reactions to form bis(pentamethylphenyl) acetic acid and a beta-carboline respectively. It is employed in the synthesis of a sulfinylmaleate, which serves as an efficient dienophile for enantioselective Diels-Alder cycloadditions.

Solubility
Soluble in water, dimethyl sulfoxide and alcohol. Insoluble in diethyl ether and hydrocarbons.

Notes
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible withbases, oxidizing agents and reducing agents.

Specifications

Chemical Identifiers

• CAS: 563-96-2
• Molecular Formula: C2H4O4
• Molecular Weight (g/mol): 92.05
• MDL Number: MFCD00149497
• InChI Key: MOOYVEVEDVVKGD-UHFFFAOYSA-N
• Synonym: glyoxylic acid monohydrate, glyoxylic acid hydrate, 2-oxoacetic acid hydrate, oxaldehydic acid hydrate, glyoxalic acid monohydrate, glyoxalate, glyoxylate hydrate, glyoxalic acid hydrate, oxoacetate monohydrate, glyoxylic acid-hydrate, oxoacetic acid hydrate
• PubChem CID: 15620607
• IUPAC Name: oxaldehydic acid;hydrate
• SMILES: C(=O)C(=O)O.O

• Melting Point: 48°C to 52°C
• Boiling Point: 100°C
• Flash Point: >110°C (230°F)
• Quantity: 25 g
• UN Number: UN3261
• Beilstein: 969535
• Sensitivity: Hygroscopic
• Merck Index: 14,4511
• Solubility Information: Soluble in water,dimethyl sulfoxide and alcohol. Insoluble in diethyl ether and hydrocarbons.
• Formula Weight: 92.06 (74.04 Anhydrous)
• Percent Purity: 97%
• Chemical Name or Material: Glyoxylic acid monohydrate

Safety and Handling

Hazard Category	H314-H317-H500
Hazard Statement	GHS H Statement H314-H318-H317 Causes severe skin burns and eye damage. Causes serious eye damage. May cause an allergic skin reaction.
Precautionary Statement	P260-P264b-P272-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P333+P313-P363-P501c
DOTInformation	Hazard Class: 8; Packaging Group: II
EINECSNumber	206-058-5
RTECSNumber	MD4550000
TSCA	Yes
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only