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GNAO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7204957 Shop All Proteintech Group Inc Products
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50-172-8132 150 μL
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Catalog No. 50-172-8132 Supplier Proteintech Group Inc Supplier No. 126351AP150UL
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Rabbit Polyclonal Antibody

Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the ′off′ state. Ligand-receptor binding results in detachment of the G protein, switching it to an ′on′ state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.

Specifications

Antigen GNAO1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GNAO1
Gene Accession No. P09471, P18872, P59215
Gene Alias G ALPHA o, GNAO, GNAO1
Gene Symbols GNAO1
Host Species Rabbit
Immunogen GNAO1 Fusion Protein Ag3330
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14681, 2775, 50664
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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