Invitrogen™ GNB3/GNB4 Polyclonal Antibody, Biotin

Catalog No.	Quantity
PIPA5142624	100 μg

Catalog No. PIPA5142624 Supplier Invitrogen™ Supplier No. PA5142624

Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize GNB3 & GNB4 (GeneID: 2784, 59345; ProteinID: NP_002066.1; NP_067642.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

Specifications

• Antigen: GNB3/GNB4
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Biotin
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: GNB3
• Gene Accession No.: P16520, Q9HAV0
• Gene Alias: 6720453A21Rik; CMTD1F; CSNB1H; G protein beta-4 subunit; G protein beta-subunit; G protein subunit beta 3; G protein subunit beta 4; G protein, beta-3 subunit; G(beta)4; gbb3; gbb4; Gnb3; Gnb-3; GNB4; G-protein beta 4 subunit; GTP-binding regulatory protein beta-3 chain; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta 4; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein (G protein), beta polypeptide 4; guanine nucleotide binding protein beta 4 subunit; guanine nucleotide binding protein, beta 3; guanine nucleotide binding protein, beta 4; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; Guanine nucleotide-binding protein subunit beta-4; guanine nucleotide-binding protein, beta-3 subunit; hypertension associated protein; transducin beta chain 3; Transducin beta chain 4
• Gene Symbols: GNB3, GNB4
• Host Species: Goat
• Immunogen: Peptide with sequence SGHDNRVSCLGVT (aa 309-321).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2784, 59345
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov