Invitrogen™ GNB5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA112707

Catalog No. 01-674-845

Description

A suggested positive control for this product is plasma membranes from rat cerebrum.

The Gb5 protein is a G protein subunit present predominantly in the central nervous system. This protein appears to be expressed in two forms, one found in the brain of 39 kDa and one found in the retina of 44 kDa. It has also been found that Gb5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes have been localized to most regions of the brain, whereas Gb1-4 exhibit no observable colocalization with RGS7, despite their widespread codistribution throughout similar neuronal networks. This antibody is specific for a peptide sequence within the D1 blade which is not found in the Gb's 1-4.

Specifications

• Antigen: GNB5
• Classification: Polyclonal
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: O14775, P62881, P62882
• Gene Symbols: Gnb5
• Immunogen: Synthetic peptide corresponding to the D1 blade of the G 5 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: Gnb5
• Gene Alias: flail; flailer; flr; G protein subunit beta 5; G protein, beta subunit 5L; G protein, beta-5 subunit; GB5; GBB5; Gbeta5; GBS; Gnb5; guanine nucleotide binding protein (G protein), beta 5; guanine nucleotide binding protein (G protein), beta polypeptide 5; guanine nucleotide binding protein, beta 5; guanine nucleotide-binding protein subunit beta-5; guanine nucleotide-binding protein, beta subunit 5L; guanine nucleotide-binding protein, beta-5 subunit; hug; transducin beta chain 5
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10681, 14697, 83579
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid