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Cayman Chemical ANTIBODY NCB-0846 5mg

Supplier: Cayman Chemical 332685 MG

A 5-HT4 agonist (Ki 69.9 nM) selective for 5-HT4 over 5-HT1 5-HT2 dopamine D2 and a1- and a2-adrenergic receptors at 1 mM but also acts as a partial antagonist at 5-HT3 (Ki 1189 nM) induces relaxation of precontracted rat esophageal thoracic muscularis mucosa preparations and enhances electrically evoked contractions in isolated guinea pig ileum (EC50s 208.4 and 73.2 nM respectively) increases antral and duodenal but not ileal or colonic motility in conscious dogs at 0.5 and 1 mg/kg increases gastric emptying in rats from 0.03-30 mg/kg
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