GPCR TGR7 Rabbit anti-Human, Polyclonal, Bioss
Rabbit Polyclonal Antibody
Manufacturer: Bioss BS15374R
DescriptionMay regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH|
|Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; Mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MRGD; MRGD G protein-coupled receptor; Mrgprd; TGR7|
|KLH conjugated synthetic peptide derived from human GPCR TGR7.|
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