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GPM6A Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550350

Catalog No. PA550350


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Description

Description

The antibody detects endogenous levels of total GPM6A protein.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Specifications

Specifications

GPM6A
Polyclonal
Unconjugated
GPM6A
Liquid
GPM6A
Fusion protein corresponding to a region derived from internal residues of human glycoprotein M6A
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1.9 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P51674
M6A, GPM6
Rabbit
IgG
100 μL
-20°C
Primary
2823
Documents
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