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Invitrogen™ GPM6A Polyclonal Antibody
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Catalog No. PA550350
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100 μL
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PA550350 100 μL
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Catalog No. PA550350 Supplier Invitrogen™ Supplier No. PA550350
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total GPM6A protein.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPM6A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene GPM6A
Gene Accession No. P35802, P51674, Q812E9
Gene Alias glycoprotein m6a; GPM6; Gpm6a; M6A; neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a-like
Gene Symbols GPM6A
Host Species Rabbit
Immunogen Fusion protein corresponding to a region derived from internal residues of human glycoprotein M6A.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234267, 2823, 306439
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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