Invitrogen™ GPR116 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102084

Catalog No. PIPA5102084

Description

Antibody detects endogenous levels of total GPR116.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.

Specifications

• Antigen: GPR116
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRF5
• Gene Alias: 8430401C09Rik; 9330185D23; ADGRF5; Adhesion G protein-coupled receptor F5; AI528491; DKFZp564O1923; FLJ90640; G protein-coupled hepta-helical receptor Ig-Hepta; G protein-coupled receptor 116; Gpr116; Gprhep; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116; Ig-Hepta; Ig-Hepta homolog; KIAA0758; KPG_001; mKIAA0758; probable G-protein coupled receptor 116
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221395, 224792
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: G5E8Q8, Q8IZF2
• Gene Symbols: ADGRF5
• Immunogen: A synthesized peptide derived from human ADGRF5(Accession Q8IZF2), corresponding to amino acid residues T1126-A1176.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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