Invitrogen™ GPR132 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA120393

Catalog No. PIPA120393

Description

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.

Specifications

• Antigen: GPR132
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR132
• Gene Alias: G protein-coupled receptor 132; G protein-coupled receptor G2A; G2 accumulation protein; G2a; GPR132; MGC99642; Probable G-protein coupled receptor 132
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29933
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9UNW8
• Gene Symbols: GPR132
• Immunogen: Synthetic peptide corresponding to the 2nd cytoplasmic loop of human G Protein-Coupled Receptor G2A.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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