Invitrogen™ GPR132 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550964

Catalog No. PA550964

Description

GPR132 Polyclonal Antibody detects endogenous levels of GPR132 protein.

GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.

Specifications

• Antigen: GPR132
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR132
• Gene Alias: G protein-coupled receptor 132; G protein-coupled receptor G2A; G2 accumulation protein; G2a; GPR132; MGC99642; Probable G-protein coupled receptor 132
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29933, 56696
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UNW8, Q9Z282
• Gene Symbols: GPR132
• Immunogen: Synthesized peptide derived from the C-terminal region of human G2A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG