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Invitrogen™ GPR17 Polyclonal Antibody
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Catalog No. PIPA3005
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100 μL
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Catalog No. Quantity
PIPA3005 100 μL
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Catalog No. PIPA3005 Supplier Invitrogen™ Supplier No. PA3005
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Description

Rabbit Polyclonal Antibody

IHC (P) analysis shows positive staining of GPR17 in human kidney tissue.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR17
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 0.05% sodium azide
Gene GPR17
Gene Accession No. Q13304
Gene Alias AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
Gene Symbols GPR17
Host Species Rabbit
Immunogen KLH conjugated Cys-SFEGKTNESSLSAKSEL.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2840
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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