Invitrogen™ GPR17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3005

Catalog No. PIPA3005

Description

IHC (P) analysis shows positive staining of GPR17 in human kidney tissue.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR17 is an orphan G protein-coupled receptor involved in orchestration of oligodendrocyte differentiation and myelination in the central nervous system. GPR17 is expressed in brain, kidney, heart and umbilical vein endothelial cells. GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.

Specifications

• Antigen: GPR17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR17
• Gene Alias: AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.05% sodium azide
• Gene Accession No.: Q13304
• Gene Symbols: GPR17
• Immunogen: KLH conjugated Cys-SFEGKTNESSLSAKSEL.
• Regulatory Status: RUO
• Gene ID (Entrez): 2840
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov