Invitrogen™ GPR176 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559018

Catalog No. PIPA559018

Description

Immunogen sequence: PPLSTVDSVS QVAPAAPVEP ETFPDKYSLQ FGFGPFELPP QWLSETRNSK KRLLPPLGNT PEELIQTKVP KVGRVERKMS RNNKV Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 89%.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR176 (G protein-coupled receptor 176), also known as HB-954, GPR or Gm1012, is a 515 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. Expressed in brain and spleen, with trace expression in kidney, GPR176 functions as an orphan receptor that is thought to play a role in signaling events throughout the cell. Containing four N-glycosylation sites, seven transmembrane domains and a large C-terminal cytosolic domain, GPR176 is encoded by a gene mapping to human chromosome 15q14.

Specifications

• Antigen: GPR176
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR176
• Gene Alias: Agr9; G protein-coupled receptor 176; Gm1012; Gpr; GPR176; G-protein coupled receptor 176; G-protein coupled receptor AGR9; HB954; HB-954; probable G-protein coupled receptor 176; putative G protein coupled receptor; RBU-15
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11245
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14439
• Gene Symbols: GPR176
• Immunogen: Recombinant protein corresponding to Human GPR176. Recombinant protein control fragment (Product #RP-102880).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG