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Invitrogen™ GPR20 Polyclonal Antibody
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Catalog No. PIPA532815
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50 μg
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PIPA532815 50 μg
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Catalog No. PIPA532815 Supplier Invitrogen™ Supplier No. PA532815
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Bovine (100%); Gorilla, Monkey, Marmoset, Mouse, Horse, Rabbit, Dog, Bat (94%); Hamster, Elephant (89%); Rat (83%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. Also, GPR20 may be involved in the control of intracellular cAMP levels and mitogenic signaling. Interestingly, GPR20 is expressed in liver and certain regions of the brain, including putamen, caudate and thalamus, but is not expressed in hypothalamus, pons and frontal cortex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR20
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene GPR20
Gene Accession No. Q99678
Gene Alias A430106B11Rik; CTD-3064M3.3; G protein-coupled receptor 20; G protein-coupled receptor 5-1; G protein-coupled receptor GPR20; Gpcr5-1; GPR20; G-protein coupled receptor 20; P2Y4
Gene Symbols GPR20
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR20.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2843, 515695
Target Species Human, Bovine
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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