Invitrogen™ GPR20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3068

Catalog No. PIPA3068

Description

PA3-068 detects GPR20 from mouse samples. PA3-068 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By Western blot, this antibody detects a 39 kDa protein corresponding to mouse GPR20. The PA3-068 antigen is the COOH-terminal amino acids of mouse GPR20 (338-358) IHILSIGSHTLTQPLTNGPEP coupled to KLH.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. Also, GPR20 may be involved in the control of intracellular cAMP levels and mitogenic signaling. Interestingly, GPR20 is expressed in liver and certain regions of the brain, including putamen, caudate and thalamus, but is not expressed in hypothalamus, pons and frontal cortex.

Specifications

• Antigen: GPR20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR20
• Gene Alias: A430106B11Rik; CTD-3064M3.3; G protein-coupled receptor 20; G protein-coupled receptor 5-1; G protein-coupled receptor GPR20; Gpcr5-1; GPR20; G-protein coupled receptor 20; P2Y4
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.02% sodium azide
• Gene Accession No.: Q8BYC4
• Gene Symbols: GPR20
• Immunogen: COOH-terminal amino acids of mouse GPR20 (338-358) IHILSIGSHTLTQPLTNGPEP coupled to KLH.
• Regulatory Status: RUO
• Gene ID (Entrez): 239530
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid