GPR37/Pael-R Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9750	150 μL

Catalog No. 50-172-9750 Supplier Proteintech Group Inc Supplier No. 148201AP150UL

Description

Rabbit Polyclonal Antibody

This antibody recognizes endogenous GPR37, which migrates as an approximately 50-55 kDa band in SDS-PAGE.

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.

Specifications

• Antigen: GPR37/Pael-R
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.31 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: GPR37
• Gene Accession No.: O15354, Q9QY42, Q9QYC6
• Gene Alias: EDNRBL, ETBR LP 1, GPR37, hET(B)R LP, PAELR, Pael-R
• Gene Symbols: GPR37
• Host Species: Rabbit
• Immunogen: GPR37/Pael-R Fusion Protein Ag6591
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 117549, 14763, 2861
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG