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Invitrogen™ GPR37 Polyclonal Antibody
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Catalog No. PIPA532826
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50 μg
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PIPA532826 50 μg
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Catalog No. PIPA532826 Supplier Invitrogen™ Supplier No. PA532826
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey, Rabbit (88%); Gibbon, Bovine (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR37
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene GPR37
Gene Accession No. O15354
Gene Alias AI848630; EDNRBL; endothelin B receptor-like protein 1; ETBR-LP-1; G protein-coupled receptor 37; G protein-coupled receptor 37 (endothelin receptor type B-like); Gpcr/cns1; Gpr37; G-protein coupled receptor 37; G-protein coupled receptor CNS1; hET(B)R-LP; Het-b-r-lp; Pael receptor; PAELR; Pael-R; parkin-associated endothelin B-like receptor; Parkin-associated endothelin receptor-like receptor; probable G-protein coupled receptor 37; prosaposin receptor GPR37
Gene Symbols GPR37
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPR37.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2861
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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