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Invitrogen™ GPS2 Recombinant Rabbit Monoclonal Antibody (HL2276)
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Catalog No. FEMA550471
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100 μL
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FEMA550471 100 μL
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Catalog No. FEMA550471 Supplier Invitrogen™ Supplier No. MA550471
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Rabbit Recombinant Monoclonal Antibody

GPS2 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
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Specifications

Antigen GPS2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL2276
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene GPS2
Gene Accession No. Q13227
Gene Alias AI505953; AMF-1; G protein pathway suppressor 2; GPS2; GPS-2
Gene Symbols GPS2
Host Species Rabbit
Immunogen Recombinant fragmemt of human GPS2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2874, 393948
Target Species Human, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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