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Invitrogen™ GPX4 Monoclonal Antibody (6I4E7)
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Catalog No. PIMA549216
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100 μg
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PIMA549216 100 μg
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Catalog No. PIMA549216 Supplier Invitrogen™ Supplier No. MA549216
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell, human CACO-2 whole cell, human 293T whole cell, human K562 whole cell. Flow: Hela cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPX4
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 6I4E7
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene GPX4
Gene Accession No. P36969
Gene Alias glutathione peroxidase 4; GP-GPx4; Gpx4; gpx-4; GSHPx-4; HGNC:4556; MCSP; mtPHGPx; Phgpx; phospholipid hydroperoxidase; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; SMDS; snGPx; snPHGPx; sperm nuclei glutathione peroxidase; sperm nucleus glutathione peroxidase
Gene Symbols GPX4
Host Species Mouse
Immunogen E.coli-derived human Glutathione Peroxidase 4/GPX4 recombinant protein (Position: A30-F197).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2879
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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