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Invitrogen™ GPX4 Recombinant Rabbit Monoclonal Antibody (JU11-31)
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Catalog No. PIMA532827 Shop All Thermo Scientific Products
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PIMA532827 100 μL
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Catalog No. PIMA532827 Supplier Invitrogen™ Supplier No. MA532827
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPX4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JU11-31
Concentration 1.064 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene GPX4
Gene Accession No. O70325, P36969, P36970
Gene Alias glutathione peroxidase 4; GP-GPx4; Gpx4; gpx-4; GSHPx-4; HGNC:4556; MCSP; mtPHGPx; Phgpx; phospholipid hydroperoxidase; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; SMDS; snGPx; snPHGPx; sperm nuclei glutathione peroxidase; sperm nucleus glutathione peroxidase
Gene Symbols GPX4
Host Species Rabbit
Immunogen Synthetic peptide within Human GPX4 aa 23-72.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2879, 29328, 625249
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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