Gram Negative Endotoxin Monoclonal Antibody (GNE10-113.3), Invitrogen™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA546031	Thermo Scientific MA546031	100μg
01-671-917	Thermo Scientific MA110686	500 μg
PIMA546081	Thermo Scientific MA546081	1 mg

Description

MA1-10686 detects Endotoxin from E. coli samples. MA1-10686 has been successfully used in ELISA applications. The MA1-10686 immunogen is E. coli serotypes: O:111, B4 J5.

Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "e;endotoxin"e; is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.

Specifications

• Antigen: Gram Negative Endotoxin
• Concentration: 2.0 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with no preservative; pH 7.4
• Isotype: IgG3
• Purification Method: PEG precipitation
• Product Type: Antibody

• Clone: GNE10-113.3
• Applications: ELISA
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Bacteria
• Immunogen: E. coli serotypes: O:111, B4 J5.
• Primary or Secondary: Primary
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles