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  6. Invitrogen™ Gram Negative Endotoxin Monoclonal Antibody (HEC10-172.5), Invitrogen™

Invitrogen™ Gram Negative Endotoxin Monoclonal Antibody (HEC10-172.5), Invitrogen™

Catalog No. PIMA546060
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Catalog No. Quantity
PIMA546060 100 μg
01-671-921 500 μg
PIMA546089 1 mg
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Catalog No. PIMA546060

Supplier: Invitrogen™ MA546060

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Description

Mouse Monoclonal Antibody

MA1-10690 detects Endotoxin from K. pneumoniae, S. marcescens, P. mirabilis, P. vulgaris, and Ps. aeruginosa samples. MA1-10690 has been successfully used in ELISA applications. The MA1-10690 immunogen is E. coli serotypes: O:111, B4 J5.

Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term 'endotoxin' is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Gram Negative Endotoxin
Applications ELISA
Classification Monoclonal
Clone HEC10-172.5
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Host Species Mouse
Immunogen E. coli serotypes: O:111, B4 J5.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Bacteria
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgM
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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