Invitrogen™ GRASP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581882

Catalog No. PIPA581882

Description

Immunogen sequence: KESSAVPARS LSSSPQAQPP RPAELSDEEV AELFQRLAET QQEKWMLEEK VKHLEVSSAS MAEDLCRKSA IIETYVMDSR IDVSVAAGHT DRSGLGSVLR DLVKPGDENL REMNK.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).

Specifications

• Antigen: GRASP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIPAP1
• Gene Alias: 30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56850
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q4V328
• Gene Symbols: GRIPAP1
• Immunogen: Recombinant protein corresponding to Human GRIPAP1. Recombinant protein control fragment (Product #RP-91910).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG