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Invitrogen™ GRASP1 Polyclonal Antibody
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Catalog No. PIPA581882
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100 μL
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PIPA581882 100 μL
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Catalog No. PIPA581882 Supplier Invitrogen™ Supplier No. PA581882
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KESSAVPARS LSSSPQAQPP RPAELSDEEV AELFQRLAET QQEKWMLEEK VKHLEVSSAS MAEDLCRKSA IIETYVMDSR IDVSVAAGHT DRSGLGSVLR DLVKPGDENL REMNK Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRASP1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GRIPAP1
Gene Accession No. Q4V328
Gene Alias 30kDa C-terminus form; AI854681; DXImx47e; Grasp1; GRASP-1; GRASP-1 C-terminal chain; GRIP1; GRIP-1; GRIP1 associated protein 1; GRIP1-associated protein 1; Gripap1; GRIP-associated protein 1; HCMV-interacting protein; Kiaa1167; mKIAA1167; MPMGp800B12492Q3; Sfc10
Gene Symbols GRIPAP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GRIPAP1. Recombinant protein control fragment (Product #RP-91910).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56850
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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