GRB10 Monoclonal Antibody (OTI6G1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA812351

Catalog No. 50-168-4529

Description

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

Specifications

• Antigen: GRB10
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q13322
• Gene Symbols: GRB10
• Immunogen: Human recombit protein fragment corresponding to amino acids 164-415 of human GRB10 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI6G1
• Conjugate: Unconjugated
• Gene: GRB10
• Gene Alias: GRB-IR, Grb-10, IRBP, MEG1, RSS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2887
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid