GRB10 Monoclonal Antibody (OTI6G1), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4529	100 μL

Catalog No. 50-168-4529 Supplier OriGene Supplier No. TA812351

Description

Mouse Monoclonal Antibody

GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.

Specifications

• Antigen: GRB10
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6G1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: GRB10
• Gene Accession No.: Q13322
• Gene Alias: GRB-IR, Grb-10, IRBP, MEG1, RSS
• Gene Symbols: GRB10
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 164-415 of human GRB10 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2887
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1