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Invitrogen™ GRB2 Recombinant Rabbit Monoclonal Antibody (6E1)
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Catalog No. PIMA538421
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100 μL
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PIMA538421 100 μL
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Catalog No. PIMA538421 Supplier Invitrogen™ Supplier No. MA538421
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody has been tested in direct-ELISA.

GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2-Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 6E1
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 150mM NaCl and 0.02% sodium azide; pH 7.4
Gene GRB2
Gene Accession No. P62993, P62994, Q60631
Gene Alias AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg
Gene Symbols GRB2
Host Species Rabbit
Immunogen A synthesized peptide derived from human GRB2.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14784, 2885, 81504
Target Species Human, Mouse, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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