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Invitrogen™ GREM2 Monoclonal Antibody (377407)
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Catalog No. MA561092
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MA561092 100 μg
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Catalog No. MA561092 Supplier Invitrogen™ Supplier No. MA561092
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Description

Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GREM2
Applications Western Blot
Classification Monoclonal
Clone 377407
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene Grem2
Gene Accession No. O88273
Gene Alias CKTSF1B2; CKTSF1B2FLJ21195; Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; DAND3; DAND3Prdc; GREM2; gremlin 2; gremlin 2 homolog, cysteine knot superfamily; gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis); gremlin 2, cysteine knot superfamily, homolog; gremlin 2, DAN family BMP antagonist; Gremlin1; Gremlin2; gremlin-2; Prdc; PRDCgremlin 2; Protein related to DAN and cerberus; RGD1560008
Gene Symbols Grem2
Host Species Rat
Immunogen E. coli-derived recombinant mouse PRDC/GREM2, Arg22-Gln168.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23893
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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