GRIP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3858	Proteintech Group Inc 223981AP150UL	150 μL

Description

GRIP1 is involved in glutamate receptors, which play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).

Specifications

• Antigen: GRIP1
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q925T6, Q9Y3R0
• Gene ID (Entrez): 23426, 74053
• Immunogen: GRIP1 Fusion Protein Ag18071
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: GRIP1

• Concentration: 0.53 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: GRIP, GRIP1
• Gene Symbols: Grip1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody