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GRK1 Monoclonal Antibody (OTI4G8), TrueMAB™, OriGene
SDP

Catalog No. 501684295
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100 μL
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Catalog No. Quantity
50-168-4295 100 μL
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Catalog No. 50-168-4295 Supplier OriGene Supplier No. TA811857
May include imposed supplier surcharges.
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Description

Mouse Monoclonal Antibody

The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin. Rhodopsin kinase is a G-protein-coupled Ser/Thr kinase, also known as GRK1, which is a key element in the regulation of this cascade. Following phosphorylation by GRK1, arrestin is recruited to phospho-rhodopsin quenching its phototransductive activity by preventing further interaction with transducin. By breaking the cycle of phototransduction, GRK1 plays an important role in the restoration of the system for subsequent visual events.

Specifications

Antigen GRK1
Applications Western Blot
Classification Monoclonal
Clone OTI4G8
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene GRK1
Gene Accession No. Q15835
Gene Alias GPRK1, RHOK, RK
Gene Symbols GRK1
Host Species Mouse
Immunogen Full length human recombit protein of human GRK1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6011
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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