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GRM8 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501732057 Shop All Proteintech Group Inc Products
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50-173-2057 150 μL
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Catalog No. 50-173-2057 Supplier Proteintech Group Inc Supplier No. 182241AP150UL
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Description

Rabbit Polyclonal Antibody

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Specifications

Antigen GRM8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene GRM8
Gene Accession No. O00222, P47743, P70579
Gene Alias GLUR8, GPRC1H, GRM8, mGlu8, MGLUR8
Gene Symbols Grm8
Host Species Rabbit
Immunogen GRM8 Fusion Protein Ag13011
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14823, 2918, 60590
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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