Invitrogen™ Growth Hormone Monoclonal Antibody (3E2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA514682

Catalog No. PIMA514682

Description

MA5-14682 targets Human Growth Hormone in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MA5-14682 immunogen is human Growth Hormone. MA5-14682 detects Human Growth Hormone which has a predicted molecular weight of approximately 24 kDa. Product MA514682 is a smaller package size of MIH9901 (formerly sold as a Seradyn product).

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

Specifications

• Antigen: Growth Hormone
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P01241
• Gene Symbols: Gh1
• Immunogen: Human Growth Hormone.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunoprecipitation, Radioimmune Assays (RIA)
• Clone: 3E2
• Conjugate: Unconjugated
• Gene: Gh1
• Gene Alias: dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; rHGH; RNGHGP; Somatotropin
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2688
• Content And Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov