Growth hormone Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5553	150 μL

Catalog No. 50-173-5553 Supplier Proteintech Group Inc Supplier No. 270791AP150UL

Description

Rabbit Polyclonal Antibody

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

Specifications

• Antigen: Growth hormone
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: GH1
• Gene Accession No.: P01241
• Gene Alias: GH, GH N, GH1, GHN, Growth hormone, growth hormone 1, hGH N, Pituitary growth hormone, Somatotropin
• Gene Symbols: GH1
• Host Species: Rabbit
• Immunogen: Growth hormone Fusion Protein Ag22841
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2688
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG