Tocris GSK 137647
Potent and selective FFA4 (GPR120) agonist
Manufacturer: Tocris 5257/50
DescriptionPotent and selective FFA4 (GPR120) agonist (pEC50 values are 6.3, 6.2 and 6.1 at the human, mouse and rat receptor, respectively). Exhibits ≥100-fold selectivity against a panel of 61 targets including FFA1, FFA2 and FFA3. Enhances glucose-stimulated insulin secretion in MIN6 cells. Induces intracellular calcium accumulation in U2OS cells; this activity is inhibited by AH 7614 (Cat. No. 5256).
- Chemical Name: 4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
- Formula: C16H19NO3S
- CAS Number: 349085-82-1
- Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
- Purity: >99
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok