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Cayman Chemical GSK205hydrobromIde 10mg
SDP

Supplier:  Cayman Chemical 4092310 MG

Encompass_Preferred

A TRPV4 and TRPA1 inhibitor (IC50s = 4.19 and 5.56, respectively, for the rat channels); inhibits GSK1016790A-induced calcium influx in whole-cell patch-clamp assays using Neuro2a cells expressing TRPV4 at 5 µM; prevents compression-induced increases in NF-κB transcriptional activity and secreted levels of IL-6 and VEGFA, as well as inhibits compression-induced fractures, abnormal cell morphology, and fissures in the intervertebral space, in primary mouse lumbar spines at 10 µM

Catalog No. 50-294-3167


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