GSTO1 Mouse anti-Human, Mouse, Rat, Clone: 5E1E10, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 601502IG150UL

Catalog No. 50-173-6264

Description

GSTO1 (glutathione S-transferase omega 1), also known as p28 or GSTTLp28, is a 241 amino acid protein that localizes to the cytoplasm and contains both an N-terminal and a C-terminal GST domain. Expressed ubiquitously with highest expression in heart, liver and skeletal muscle, GSTO1 exists as a homodimer that functions as both a glutathione-dependent thiol transferase and a dehydroascorbate reductase. Specifically, GSTO1 catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a process that is essential for the metabolism and detoxification of a variety of xenobiotics and carcinogens. Human GSTO1 shares 70% sequence homology with its rodent counterpart, suggesting a conserved role between species. Polymorphisms in the gene encoding GSTO1 may be associated with the development of childhood acute lymphoblastic leukemia, Parkinson′s disease and Alzheimer disease.

Specifications

• Antigen: GSTO1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: O09131, P78417, Q9Z339
• Gene Symbols: Gsto1
• Immunogen: GSTO1 Fusion Protein Ag7199
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5E1E10
• Conjugate: Unconjugated
• Gene: GSTO1
• Gene Alias: glutathione S transferase omega 1, GSTO 1, GSTO1
• Host Species: Mouse
• Purification Method: Caprylic Acid Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 114846, 14873, 9446
• Content And Storage: -20°C
• Form: Liquid