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GTPBP4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. p-7205621 Shop All Proteintech Group Inc Products
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50-172-9074 150 μL
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Catalog No. 50-172-9074 Supplier Proteintech Group Inc Supplier No. 138971AP150UL
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Rabbit Polyclonal Antibody

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. ′Active′ in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Specifications

Antigen GTPBP4
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GTPBP4
Gene Accession No. Q99ME9, Q9BZE4
Gene Alias CRFG, GTP binding protein 4, GTP binding protein NGB, GTPBP4, NGB, NOG1
Gene Symbols Gtpbp4
Host Species Rabbit
Immunogen GTPBP4 Fusion Protein Ag4859
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23560, 69237
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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